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促红细胞生成素:红细胞分化的主要调节因子。

Erythropoietin: a prime regulator of red cell differentiation.

作者信息

Sytkowski A J

出版信息

Biomed Pharmacother. 1984;38(8):369-71.

PMID:6525433
Abstract

Erythropoietin, a glycoprotein hormone that regulates erythroid differentiation, has been recognized for several decades. Recently, the study of this hormone has increased markedly. It has been purified and partially sequenced. There are several monoclonal and site-specific polyclonal antibodies to it that have revealed important structural information. The gene appears to have been cloned. Current efforts to understand its mode of action will yield answers to questions of importance to both basic scientists and clinicians.

摘要

促红细胞生成素是一种调节红细胞分化的糖蛋白激素,几十年来一直为人们所熟知。最近,对这种激素的研究显著增加。它已被纯化并进行了部分测序。有几种针对它的单克隆抗体和位点特异性多克隆抗体,这些抗体揭示了重要的结构信息。该基因似乎已被克隆。目前为了解其作用方式所做的努力将为基础科学家和临床医生都关心的重要问题提供答案。

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