Sugimoto T, Takemura M, Okubo J, Sakai A
Brain Res. 1984 Dec 10;323(2):320-5. doi: 10.1016/0006-8993(84)90306-8.
The effect of transection of the inferior alveolar nerve on the trigeminal subnucleus caudalis neuron was examined under the influence of systemic strychnine in the rat. Chronic intoxication with a subconvulsive dose of strychnine induced electron dense degeneration of somata and dendrites at 30 days following transection in the area of subnucleus caudalis which received primary projection from the transected nerve. Removal of the postsynaptic inhibition appears to enhance the transneuronal effect of peripheral nerve injury.
在大鼠全身注射士的宁的影响下，研究了切断下牙槽神经对三叉神经尾侧亚核神经元的作用。在切断神经后30天，用亚惊厥剂量的士的宁进行慢性中毒，导致接受切断神经初级投射的尾侧亚核区域的神经元胞体和树突出现电子致密性变性。突触后抑制的消除似乎增强了周围神经损伤的跨神经元效应。
