Guerrera C, Gasbarro V, Rubbini M, Pozza E, De Anna D, Tartari V, Bignami R, Nigro Imperiale F
Chir Ital. 1984 Apr;36(2):194-203.
The authors report their experience concerning 26 cases of gastric stump carcinoma after gastric resection for benign pathology, observed in about 12 years. The incidence of such disease is 9,2% as regards the gastric neoplastic pathology and 5,2% as regards the benign ulcerous pathology, observed in the same period of time. The removal of the tumour was performed in 18 cases (69,2%), in spite of the stage, in most cases advanced, of the disease. In 7 cases (38,8%) the operation was extended to other organs. In 5 cases (27,7%) the removal was performed in spite of the presence of liver metastases. The survival amounts to 3 (16,6%) patients after 2, 4,5 and 5 years, one of whom suffers from liver metastases. In spite of the better knowledge of the histologic modifications and the phenomena caused by the biliopancreatic rebux and gastric hypochlorhydria, the etiopathogenesis of that disease is still unknown; the prognosis remains still unfavourable, due to the diagnostical delay and the particular aggressiveness of the neoplasm. Therefore, the Authors confirm the necessity for a precocious diagnosis, which only is suitable to improve the immediate and remote results.
作者报告了他们在约12年中观察到的26例因良性病变行胃切除术后发生残胃癌的病例。该疾病在同期胃肿瘤病理学中的发病率为9.2%,在良性溃疡病理学中的发病率为5.2%。尽管大多数病例疾病处于晚期,但仍有18例(69.2%)进行了肿瘤切除。7例(38.8%)手术范围扩大至其他器官。5例(27.7%)尽管存在肝转移仍进行了切除。2年、4年、5年和5年后分别有3例(16.6%)患者存活,其中1例有肝转移。尽管对胆胰反流和胃低氯血症引起的组织学改变及现象有了更好的了解,但该疾病的病因发病机制仍不清楚;由于诊断延迟和肿瘤的特殊侵袭性,预后仍然不佳。因此,作者确认有必要进行早期诊断,这是改善近期和远期结果的唯一合适方法。