Prognostic factors in chronic lymphocytic leukemia.

In respect to literary data, we tried to evaluate some qualitative and quantitative indices for prognosis of chronic lymphocytic leukemia (CLL). In the group of 117 patients we evaluated prognostic parameter proposed by Jaksic and Vitale, which takes into consideration so-called total tumour mass (TTM). In the group of patients investigated we did not succeed in confirmation of prognostic value of TTM scoring as determined at the time of CLL diagnosis. However, investigation of doubling time of total tumour mass (DT TTM) appeared to be more important. To determine reliable prognostic criteria for CLL, however, complex cooperative study on the greater group of patients is necessary.