Crepaz R, Tezzon F, Erlicher A, Vedovello R, Pitscheider W, Lintner W, Moresco W, Oberlechner W, Braito E
G Ital Cardiol. 1984 Nov;14(11):847-51.
Nine patients, 7 males, 2 females, mean age 36 years, with myotonic muscular dystrophy who had no cardiac symptoms underwent M-mode echocardiography (e.), systolic time intervals (STI) measurement by simultaneous recordings of the electrocardiogram, phonocardiogram and carotid arterial pulse, and single-pass radionuclide angiocardiography (RNA) in order to assess the left ventricular function. The ejecting phase indexes measured by echocardiography (fractional shortening, mean velocity of circumferential fiber shortening) were slightly depressed in 1 case and an abnormal PEP/LVET ratio was found in 3 cases. The ejection fraction measured by radionuclide angiocardiography was abnormal in 1 case who showed a diffuse hypokinesia. The IVI%, a new isovolumic phase index obtained by echocardiography, was abnormal in all patients. It is concluded that the IVI% seems more sensitive than the ejecting phase indexes calculated by echocardiography or radionuclide angiocardiography and the PEP/LVET ratio in detecting abnormalities of left ventricular function in patients with myotonic muscular dystrophy and no clinical signs of heart disease.
9例患者，男性7例，女性2例，平均年龄36岁，患有强直性肌营养不良，无心脏症状，接受了M型超声心动图检查、通过同步记录心电图、心音图和颈动脉脉搏测量收缩期时间间期（STI）以及单通道放射性核素血管造影（RNA），以评估左心室功能。通过超声心动图测量的射血期指标（缩短分数、圆周纤维缩短平均速度）在1例中略有降低，3例中发现异常的PEP/LVET比值。放射性核素血管造影测量的射血分数在1例表现为弥漫性运动减弱的患者中异常。通过超声心动图获得的新的等容期指标IVI%在所有患者中均异常。结论是，在检测无心脏病临床体征的强直性肌营养不良患者左心室功能异常方面，IVI%似乎比超声心动图或放射性核素血管造影计算的射血期指标以及PEP/LVET比值更敏感。
