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来自非洲爪蟾皮肤的蛙皮素mRNA的一种异常重复结构。

An unusual repetitive structure of caerulein mRNA from the skin of Xenopus laevis.

作者信息

Wakabayashi T, Kato H, Tachibana S

出版信息

Gene. 1984 Nov;31(1-3):295-9. doi: 10.1016/0378-1119(84)90225-7.

DOI:10.1016/0378-1119(84)90225-7
PMID:6526274
Abstract

The nucleotide sequence of a 784-bp segment of cloned caerulein mRNA obtained from the skin of Xenopus laevis was determined. It codes for five heterogeneous procaerulein peptides interspersed with three 147-bp intercaerulein segments (ICS). The ICSs contain six inverted repeats and five eukaryotic enhancer-like sequences. Evidence for the presence of multiple forms of caerulein mRNA is presented.

摘要

测定了从非洲爪蟾皮肤中获得的克隆蛙皮素mRNA的一段784个碱基对片段的核苷酸序列。它编码五个异源前蛙皮素肽,其间穿插着三个147个碱基对的蛙皮素间插序列(ICS)。这些ICS包含六个反向重复序列和五个真核增强子样序列。文中给出了存在多种形式蛙皮素mRNA的证据。

相似文献

1
An unusual repetitive structure of caerulein mRNA from the skin of Xenopus laevis.来自非洲爪蟾皮肤的蛙皮素mRNA的一种异常重复结构。
Gene. 1984 Nov;31(1-3):295-9. doi: 10.1016/0378-1119(84)90225-7.
2
Complete nucleotide sequence of mRNA for caerulein precursor from Xenopus skin: the mRNA contains an unusual repetitive structure.非洲爪蟾皮肤中蛙皮素前体mRNA的完整核苷酸序列:该mRNA含有一种异常的重复结构。
Nucleic Acids Res. 1985 Mar 25;13(6):1817-28. doi: 10.1093/nar/13.6.1817.
3
Biosynthesis of caerulein in the skin of Xenopus laevis: partial sequences of precursors as deduced from cDNA clones.非洲爪蟾皮肤中蛙皮素的生物合成:从cDNA克隆推导的前体部分序列
EMBO J. 1983;2(1):111-4. doi: 10.1002/j.1460-2075.1983.tb01390.x.
4
Sequence of preprocaerulein cDNAs cloned from skin of Xenopus laevis. A small family of precursors containing one, three, or four copies of the final product.从非洲爪蟾皮肤中克隆的前降钙素原cDNA序列。一个包含最终产物一、三或四个拷贝的前体小家族。
J Biol Chem. 1986 Mar 15;261(8):3676-80.
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Structure of two cDNAs encoding cholecystokinin precursors from the brain of Xenopus laevis.来自非洲爪蟾大脑的编码胆囊收缩素前体的两个互补脱氧核糖核酸的结构。
J Mol Endocrinol. 1995 Jun;14(3):357-64. doi: 10.1677/jme.0.0140357.
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Biosynthesis of peptides in the skin of Xenopus laevis: isolation of novel peptides predicted from the sequence of cloned cDNAs.非洲爪蟾皮肤中肽的生物合成:从克隆的cDNA序列预测的新型肽的分离
Peptides. 1985;6 Suppl 3:17-21. doi: 10.1016/0196-9781(85)90345-6.
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Relationship of promagainin to three other prohormones from the skin of Xenopus laevis: a different perspective.非洲爪蟾皮肤中前蛙皮素与其他三种前激素的关系:一个不同的视角。
FEBS Lett. 1988 Jun 20;233(2):282-8. doi: 10.1016/0014-5793(88)80443-5.
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Conserved exon-intron organization in two different caerulein precursor genes of Xenopus laevis. Additional detection of an exon potentially coding for a new peptide.非洲爪蟾两种不同蛙皮素前体基因中保守的外显子-内含子结构。额外检测到一个可能编码新肽段的外显子。
Eur J Biochem. 1987 Nov 16;169(1):53-8. doi: 10.1111/j.1432-1033.1987.tb13579.x.
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The genes for the frog skin peptides GLa, xenopsin, levitide and caerulein contain a homologous export exon encoding a signal sequence and part of an amphiphilic peptide.
Eur J Biochem. 1989 Feb 1;179(2):281-5. doi: 10.1111/j.1432-1033.1989.tb14552.x.
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The cDNA sequence coding for prepro-PGS (prepro-magainins) and aspects of the processing of this prepro-polypeptide.编码前原PGS(前原蛙皮素)的cDNA序列以及该前原多肽的加工过程的各个方面。
J Biol Chem. 1988 Apr 25;263(12):5745-51.

引用本文的文献

1
Complete nucleotide sequence of mRNA for caerulein precursor from Xenopus skin: the mRNA contains an unusual repetitive structure.非洲爪蟾皮肤中蛙皮素前体mRNA的完整核苷酸序列:该mRNA含有一种异常的重复结构。
Nucleic Acids Res. 1985 Mar 25;13(6):1817-28. doi: 10.1093/nar/13.6.1817.
2
Development of Xenopus laevis skin glands producing 5-hydroxytryptamine and caerulein.非洲爪蟾产生5-羟色胺和蛙皮素的皮肤腺体的发育
Cell Tissue Res. 1989 Dec;258(3):483-9. doi: 10.1007/BF00218860.