Daróczy J
Hautarzt. 1984 Dec;35(12):630-9.
The structure and function of the dermal lymphatics are described. The lymphatic system is considered to be an important part of the dermal microvascularisation. The characteristic ultrastructural features of the lymphatics were studied by electron microscopy. The lymphatic endothelial walls are closely connected with the connective tissue (interrupted basal lamina, lack of pericytes, elastic lamina and muscle cells), which makes possible the direct transmission of the pressure changes of the interstitial space to the initial lymphatics. The capillaries can change their dilatation rate due to the loose connection of the endothelial cells. The capillaries work like a piston. The valves (inlet and intralymphatic valves) ensure the centripetal lymph flow. It is assumed that the valves can change their form and position and that the intralymphatic valves (unicellular- and bunch valves) are rebuilt in order to fulfill the new requirements of the pressure variations. These valves help to direct the lymph flow. If the valve system is partially or completely insufficient, dermal lymph edema can develop.
描述了真皮淋巴管的结构和功能。淋巴系统被认为是真皮微血管化的重要组成部分。通过电子显微镜研究了淋巴管的特征性超微结构特征。淋巴管内皮壁与结缔组织紧密相连(基底膜中断、缺乏周细胞、弹性膜和肌肉细胞),这使得间质空间的压力变化能够直接传递到初始淋巴管。由于内皮细胞连接松散,毛细血管可以改变其扩张率。毛细血管的工作方式类似于活塞。瓣膜(入口瓣膜和淋巴管内瓣膜)确保淋巴向心流动。据推测,瓣膜可以改变其形态和位置,并且淋巴管内瓣膜(单细胞瓣膜和成束瓣膜)会进行重塑以满足压力变化的新要求。这些瓣膜有助于引导淋巴流动。如果瓣膜系统部分或完全功能不全,可能会发生真皮淋巴水肿。