Sharmanov T Sh, Abdraimova S M, Abdrashitova E Kh, Maksimenko V B, Tazhibaev Sh S
Vopr Med Khim. 1984 Sep-Oct;30(5):114-8.
Long-term hypokinesia of August and Wistar Albino Glasgow rats caused some alterations in composition of total lipids and cholesterol esters both in blood serum and in individual lipoprotein fractions. The most distinct alterations were the following ones: I. increase in content of very low density lipoproteins (VLDL) and of low density lipoproteins (LDL), 2. decrease in the level of cholesterol esters in blood serum with a simultaneous increase of their content in VLDL and LDL as well as with alteration of their composition, 3. decrease of triglyceride content in VLDL and increase--in LDL, exhibiting the alteration in activity of lipolytic enzymes. Functional activity of muscles was very important for maintaining of the normal level of blood serum lipids and lipoproteins.
八月龄大鼠和Wistar白化格拉斯哥大鼠的长期运动减退导致血清及各脂蛋白组分中的总脂质和胆固醇酯成分发生了一些变化。最明显的变化如下:1. 极低密度脂蛋白(VLDL)和低密度脂蛋白(LDL)含量增加;2. 血清中胆固醇酯水平降低,同时VLDL和LDL中胆固醇酯含量增加且其组成发生改变;3. VLDL中甘油三酯含量降低,LDL中甘油三酯含量增加,这表明脂解酶活性发生了改变。肌肉的功能活动对于维持血清脂质和脂蛋白的正常水平非常重要。