Harzer K
Z Rechtsmed. 1984;93(3):181-5. doi: 10.1007/BF00200448.
In two cases, after i.v. injections of colchicine serum concentrations of 170 ng/ml and 240 ng/ml were found before death. Colchicine was extracted from serum with the aid of Extrelut extraction columns and analysed using HPLC. Urine was also analysed and the findings were confirmed by drawing a UV-curve for colchicine using the stop-flow method. In one case, colchicine was still detectable in urine 10 days after injection.
在两起案例中,静脉注射秋水仙碱后,死亡前血清浓度分别为170纳克/毫升和240纳克/毫升。借助于埃克斯特路特萃取柱从血清中提取秋水仙碱,并使用高效液相色谱法进行分析。同时也对尿液进行了分析,并通过停流法绘制秋水仙碱的紫外曲线来证实分析结果。在其中一个案例中,注射10天后尿液中仍可检测到秋水仙碱。