Sánchez Palacios A, Quintero de Juana A, Martínez Sagarra J, Aparicio Duque R
Allergol Immunopathol (Madr). 1984 Nov-Dec;12(6):463-9.
In this work we study a case of eosinophilic cystitis induced by the ingestion of some specific foodstuffs (tomatoes, coffee, carrots) and strong smells (petrol) in a female patient with clinical history of extrinsic permanent rhinitis and Quincke's oedema. Skin tests and RAST showed specific antibodies against Dermatophagoides Pteronyssimus, Farinae, Alternaria and Cladosporium. These antigens were related to the rhinosinusitis and facial oedema. Provocative tests were used to make the definitive diagnosis. They were carried out when the patient was symptomless and the following parameters were taken into account: the time elapsed estil the appearance of the symptoms, the intensity of urinary symptoms, polakiuria, urgency and prepubic pain, cystoscopy, bladder histology, urine volume and pre-and post-test histaminuria in 24 hours. Bladder histology subsequent to the intake of tomato showed capillary congestion and severe inflammatory infiltration with a clear predominance of eosinophils. The histaminuria values after the ingestion of tomatoes, carrots and coffee were superior to basal determinations, amounting to a maximum of 1229 mcg./l. in 24 hours. The allergic origin of these eosinophilic cystitis is proved by the appearance of urologic symptoms and eosinophilic infiltration of the bladder subsequent to provocative tests, which subside when the antigens which bring them about are removed.
在这项研究中，我们探讨了一名患有外源性持续性鼻炎和昆克水肿病史的女性患者，因摄入某些特定食物（西红柿、咖啡、胡萝卜）和强烈气味（汽油）引发嗜酸性膀胱炎的病例。皮肤试验和放射性变应原吸附试验显示，患者体内存在针对粉尘螨、粉螨、链格孢属和枝孢属的特异性抗体。这些抗原与鼻窦炎和面部水肿有关。采用激发试验进行明确诊断。激发试验在患者无症状时进行，并考虑以下参数：症状出现的时间、泌尿系统症状的强度、尿频、尿急和耻骨前疼痛、膀胱镜检查、膀胱组织学、尿量以及24小时尿液组胺测定的前后值。摄入西红柿后膀胱组织学检查显示毛细血管充血和严重炎症浸润，嗜酸性粒细胞明显占优势。摄入西红柿、胡萝卜和咖啡后的组胺尿值高于基础测定值，24小时内最高可达1229微克/升。激发试验后出现泌尿系统症状以及膀胱嗜酸性粒细胞浸润，而去除引发这些症状的抗原后症状消退，证实了这些嗜酸性膀胱炎的过敏起源。
