Vercesi A E, Pereira-da-Silva L
Braz J Med Biol Res. 1984;17(3-4):353-6.
It has been shown that Ca2+ efflux from respiring liver mitochondria is promoted by the oxidized steady state of mitochondrial pyridine nucleotides (NAD(P)), whereas Ca2+ retention is favored by a more reduced state (Lehninger, A.L., Vercesi, A.E. and Bababunmi, E.A., Proceedings of the National Academy of Sciences USA, 75, 1690-1694, 1978). The physiological relevance and the molecular mechanism responsible for the process are controversial and are discussed here.
研究表明，线粒体吡啶核苷酸（NAD(P)）的氧化稳态可促进呼吸作用的肝脏线粒体中Ca2+外流，而Ca2+保留则更倾向于还原态（Lehninger, A.L., Vercesi, A.E.和Bababunmi, E.A.，《美国国家科学院院刊》，75, 1690 - 1694, 1978）。该过程的生理相关性和分子机制存在争议，本文将对此进行讨论。
