Adams E M, Hafez G R, Carnes M, Wiesner J K, Graziano F M
Clin Exp Rheumatol. 1984 Jul-Sep;2(3):205-8.
A 58 year old female was evaluated for fever, rash, myalgias, muscle weakness and cervical lymphadenopathy. She was found to have myositis on muscle biopsy, toxoplasmic lymphadenitis on lymph node biopsy, and markedly elevated IgM and IgG antibody titers to Toxoplasma gondii. The patient was treated with prednisone and a 2 month course of sulfadiazine and pyrimethamine. The patient improved over the next six months and has been followed for approximately a five year period. During this time, antibody levels to the toxoplasma antigen have significantly decreased but the patient has developed a chronic myositis indistinguishable from polymyositis.
一名58岁女性因发热、皮疹、肌痛、肌肉无力和颈部淋巴结肿大接受评估。肌肉活检发现她患有肌炎，淋巴结活检发现弓形虫性淋巴结炎，并且弓形虫IgM和IgG抗体滴度显著升高。该患者接受了泼尼松以及为期2个月的磺胺嘧啶和乙胺嘧啶治疗。患者在接下来的6个月中病情好转，并已接受了约5年的随访。在此期间，针对弓形虫抗原的抗体水平显著下降，但患者发展出了一种与多发性肌炎难以区分的慢性肌炎。
