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Among 30 agoraphobic subjects with panic attacks, 6 presented an abnormal dexamethasone suppression test. In non suppressor patients there was a statistical trend towards an excess of major depressive disorders, and of depression in first degree relatives. It suggests that agoraphobia with panic attacks might be a heterogeneous entity. Some agoraphobias with panic attacks might be more related to endogenous depression than to anxiety states.
在30名伴有惊恐发作的广场恐惧症患者中,6人地塞米松抑制试验异常。在非抑制者中,重度抑郁症以及一级亲属患抑郁症的比例有统计学上的增高趋势。这表明伴有惊恐发作的广场恐惧症可能是一种异质性疾病。一些伴有惊恐发作的广场恐惧症可能与内源性抑郁症的关系比与焦虑状态的关系更大。