广场恐怖症中的地塞米松抑制试验。

The dexamethasone suppression test in agoraphobia.

作者信息

Peterson G A, Ballenger J C, Cox D P, Hucek A, Lydiard R B, Laraia M T, Trockman C

出版信息

J Clin Psychopharmacol. 1985 Apr;5(2):100-2. doi: 10.1097/00004714-198504000-00008.

DOI:10.1097/00004714-198504000-00008

Abstract

Patients diagnosed as having agoraphobia with panic attacks by DSM-III criteria were evaluated with the dexamethasone suppression test (DST). Depressive symptoms were assessed using the Beck Depression Inventory, the Depression Scale of the Minnesota Multiphasic Personality Inventory, and the Hamilton Rating Scale for Depression. Of 97 patients tested, 12.4% had a positive DST. These findings are consistent with earlier reports that found an incidence of abnormal DSTs between 11% and 15% in agoraphobic patients. Abnormal DSTs did not correlate with levels of depression on any of the depression measures.

摘要

按照《精神疾病诊断与统计手册》第三版（DSM - III）标准被诊断为伴有惊恐发作的广场恐惧症患者，接受了地塞米松抑制试验（DST）评估。使用贝克抑郁量表、明尼苏达多相人格调查表抑郁量表以及汉密尔顿抑郁评定量表对抑郁症状进行了评估。在接受测试的97名患者中，12.4%的患者地塞米松抑制试验结果呈阳性。这些发现与早期报告一致，早期报告发现在广场恐惧症患者中，地塞米松抑制试验异常的发生率在11%至15%之间。地塞米松抑制试验异常与任何抑郁测量指标的抑郁水平均无相关性。