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针对金黄色葡萄球菌17A的h1凝集原的单克隆抗体。用标准菌株进行血清学检测。

Monoclonal antibodies to the h1 agglutinogen from Staphylococcus aureus 17A. Serological testing with type strains.

作者信息

Haaheim L R, Lund H

出版信息

Acta Pathol Microbiol Immunol Scand B. 1984 Dec;92(6):325-30. doi: 10.1111/j.1699-0463.1984.tb02841.x.

Abstract

Four monoclonal antibodies to the h1 agglutinogen were produced by conventional means, and slide agglutination of S. aureus type strains was performed with protein A affinity purified IgG1 antibodies. In accordance with Oeding's serotype system the type strains 17A and 670 were strongly and consistently agglutinated. In addition, however, several of the remaining twelve type strains investigated showed varying reaction patterns. Our results indicate that the h1 agglutinogen may be more widely distributed among S. aureus strains than previously assumed.

摘要

通过常规方法制备了四种针对h1凝集原的单克隆抗体,并用蛋白A亲和纯化的IgG1抗体对金黄色葡萄球菌标准菌株进行玻片凝集试验。根据奥丁血清型系统,17A和670标准菌株被强烈且持续地凝集。然而,此外,所研究的其余12种标准菌株中有几种表现出不同的反应模式。我们的结果表明,h1凝集原在金黄色葡萄球菌菌株中的分布可能比之前认为的更为广泛。

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