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角膜上皮发育异常。

Corneal epithelial dysplasia.

作者信息

Roberson M C

出版信息

Ann Ophthalmol. 1984 Dec;16(12):1147-50.

PMID:6532289
Abstract

Corneal epithelial dysplasia without an identifiable limbal mass is an entity that is frequently overlooked in the differential diagnosis of chronic corneal epithelial disease. It is characterized by unilateral chronic irritative symptoms, decreased visual acuity, decreased sensation in the affected areas, and a somewhat characteristic appearance to the affected corneal epithelium. Mechanical debridement of the epithelium brings prompt relief from the symptoms, but recurrences are common. It appears that this entity is not widely recognized and should be considered in cases of chronic corneal epithelial disease of obscure etiology.

摘要

无明显角膜缘肿物的角膜上皮发育异常是一种在慢性角膜上皮疾病鉴别诊断中常被忽视的病症。其特征为单侧慢性刺激症状、视力下降、患区感觉减退以及患侧角膜上皮呈现出一定的特征性外观。上皮的机械清创能迅速缓解症状,但复发很常见。看来这种病症尚未得到广泛认识,在病因不明的慢性角膜上皮疾病病例中应予以考虑。

相似文献

1
Corneal epithelial dysplasia.角膜上皮发育异常。
Ann Ophthalmol. 1984 Dec;16(12):1147-50.
2
Corneal epithelial dysplasia.角膜上皮发育异常
Ann Ophthalmol. 1985 Jan;17(1):27-31.
3
Unilateral corneal intraepithelial neoplasia: management of the recurrent lesion.单侧角膜上皮内瘤变:复发性病变的管理
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4
The role of limbal stem cells in corneal epithelial maintenance: testing the dogma.角膜缘干细胞在角膜上皮维持中的作用:对传统观念的验证
Ophthalmology. 2009 May;116(5):856-63. doi: 10.1016/j.ophtha.2008.12.017.
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Epithelial transplantation for the management of severe ocular surface disease.上皮移植治疗严重眼表疾病
Trans Am Ophthalmol Soc. 1996;94:677-743.
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Amniotic membrane transplantation with conjunctival limbal autograft for total limbal stem cell deficiency.羊膜移植联合自体结膜角膜缘移植治疗全角膜缘干细胞缺乏症
Ophthalmology. 2003 Aug;110(8):1585-92. doi: 10.1016/S0161-6420(03)00503-7.
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Alcohol delamination of the corneal epithelium: an alternative in the management of recurrent corneal erosions.角膜上皮酒精分层:复发性角膜糜烂治疗的一种替代方法。
Ophthalmology. 2006 Mar;113(3):404-11. doi: 10.1016/j.ophtha.2005.10.049. Epub 2006 Jan 20.
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Limbal allografting from related live donors for corneal surface reconstruction.来自相关活体供体的角膜缘移植用于角膜表面重建。
Ophthalmology. 1999 Apr;106(4):822-8. doi: 10.1016/S0161-6420(99)90173-2.
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Characterization of the corneal surface in limbal stem cell deficiency and after transplantation of cultivated limbal epithelium.角膜缘干细胞缺乏症及培养角膜缘上皮移植后的角膜表面特征
Ophthalmology. 2009 Jun;116(6):1048-56. doi: 10.1016/j.ophtha.2009.01.005. Epub 2009 Apr 25.
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A case of bilateral corneal epithelial dysplasia characterized by laser confocal biomicroscopy and cytokeratin immunofluorescence.
Cornea. 2008 Jan;27(1):107-10. doi: 10.1097/ICO.0b013e318158340e.

引用本文的文献

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Corneal ocular surface squamous neoplasia: Case series and review of literature.角膜眼表鳞状上皮肿瘤:病例系列及文献综述
Oman J Ophthalmol. 2024 Jun 27;17(2):249-253. doi: 10.4103/ojo.ojo_111_23. eCollection 2024 May-Aug.
2
[Squamous cell carcinoma of the "pure" cornea].[“单纯”角膜鳞状细胞癌]
Ophthalmologe. 2009 Sep;106(9):826-8. doi: 10.1007/s00347-008-1883-z.
3
Presumed corneal intraepithelial neoplasia associated with contact lens wear and intense ultraviolet light exposure.推测与隐形眼镜佩戴及高强度紫外线暴露相关的角膜上皮内瘤变
Br J Ophthalmol. 1993 Mar;77(3):191-2. doi: 10.1136/bjo.77.3.191.
4
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.一种主要的64K角膜角蛋白在体内和体外培养中的分化相关表达提示角膜上皮干细胞位于角膜缘。
J Cell Biol. 1986 Jul;103(1):49-62. doi: 10.1083/jcb.103.1.49.
5
Beta radiation of recurrent corneal intraepithelial neoplasia.
Trans Am Ophthalmol Soc. 1991;89:285-98; discussion 298-301.