澳大利亚本土野花中的凝集素——卡罗尼羊蹄甲、康氏硬叶豆、倒卵叶毛耳草和粗叶拉多加草中凝集素的检测

Lectins from indigenous Australian wildflowers--detection of lectins from Bauhinia carronii, Hardenbergia comptoniana, Ptilotis obovatus and Rhadogia crassifolia.

作者信息

Flower R L, Wilcox G E, Chugg V, Neal J R

出版信息

Aust J Exp Biol Med Sci. 1984 Dec;62 ( Pt 6):763-9. doi: 10.1038/icb.1984.72.

DOI:10.1038/icb.1984.72

Abstract

Extracts from 21 indigenous Australian plant species, representing eight genera, were tested for haemagglutinating activity to human and animal erythrocytes. Extracts from Bauhinia carronii, Hardenbergia comptoniana, Ptilotis obovatus and Rhadogia crassifolia agglutinated at least one of the erythrocyte types tested. The extracts from B. carronii and R. crassifolia contained mitogens for human lymphocytes. Both the haemagglutinating and mitogenic activity of the B. carronii extract were inhibited by lactose. Both the haemagglutinating and mitogenic activity of R. crassifolia were inhibited by maltose and alpha-methyl-glucoside. The haemagglutinating activity of H. comptoniana was inhibited by raffinose and the haemagglutinating activity of P. obovatus by maltose and alpha-methylglucoside.

摘要

对代表八个属的21种澳大利亚本土植物物种的提取物进行了针对人类和动物红细胞的血凝活性测试。来自卡罗尼羊蹄甲、康氏硬叶豆、倒卵形毛耳草和粗叶拉多吉草的提取物凝集了至少一种所测试的红细胞类型。卡罗尼羊蹄甲和粗叶拉多吉草的提取物含有对人淋巴细胞的有丝分裂原。卡罗尼羊蹄甲提取物的血凝和有丝分裂活性均被乳糖抑制。粗叶拉多吉草的血凝和有丝分裂活性均被麦芽糖和α-甲基葡萄糖苷抑制。康氏硬叶豆的血凝活性被棉子糖抑制，倒卵形毛耳草的血凝活性被麦芽糖和α-甲基葡萄糖苷抑制。