Pallotta R, Nardi R, Del Vomano E, Elicio S, Milillo F
Pediatr Med Chir. 1984 May-Jun;6(3):401-3.
The evaluation of metacarpophalangeal profiles (MPP) and dermathoglyphics patterns in two families affected by Crouzon's syndrome differing from genic expressivity, showed indicative findings for brachidactyly and "broad thumb and hallux" character. These abnormalities show Crouzon's disease not to be a true craniofacial dysostosis and number it among the wide sphere of syndromes presenting acrocephalic alterations.
对两个患克鲁宗综合征且基因表达不同的家族中的掌指轮廓(MPP)和皮纹模式进行评估,结果显示了短指畸形和“拇指及拇趾粗大”特征的指示性发现。这些异常表明克鲁宗病并非真正的颅面骨发育不全,并将其归入呈现尖头改变的广泛综合征范畴。