Kuś H, Jarosz-Cichulska H, Staniszewska-Kuś J
Polim Med. 1984;14(1-4):13-20.
Within the research on improving polyester vascular prostheses DALLON there was made a superficial alkaline hydrolysis in the manufactured product, which greatly enhanced the prostheses wettability without lowering their resistance parameters. In preliminary laboratory research and in biological studies in vitro, made with model prostheses and with those having been hydrolyzed, the results were better for hydrolized ones. Biological studies in vivo were made on piglets by implanting the prostheses into surgical defects of the thoracic aorta. In the course of the operations it was found that the prostheses were, apart from having better wettability, far more tight intraoperationally, as compared to the model ones. Pathomorphological studies, carried out 3 and 6 months after the operation, showed that, besides the hydrolized prostheses being less calcified, there were no significant qualitative and quantitative changes in the tissues around the implanted prostheses.
在改进聚酯血管假体DALLON的研究中，对制成的产品进行了表面碱性水解，这大大提高了假体的润湿性，同时又不降低其阻力参数。在初步的实验室研究以及用模型假体和水解后的假体进行的体外生物学研究中，水解后的假体效果更好。通过将假体植入仔猪胸主动脉的手术缺损处，对仔猪进行了体内生物学研究。在手术过程中发现，与模型假体相比，这些假体除了具有更好的润湿性外，在手术中贴合得多。在术后3个月和6个月进行的病理形态学研究表明，除了水解后的假体钙化较少外，植入假体周围的组织在质和量上没有明显变化。
