Westlie L, Umen A, Nestrud S, Kjellstrand C M
Trans Am Soc Artif Intern Organs. 1984;30:21-30.
The average age of dialysis patients is rapidly increasing. In our present program, 20-25% of all patients are 70 yrs or older. We performed survival analysis of all 157 patients 70 yrs and above (mean age 75 yrs) and evaluated risk factors associated with dialysis survival using the Cox proportional hazards model. Morbidity, biochemical status, clinical results and life satisfaction were evaluated in a prevalence study of all 53 in-center and 26 home dialysis patients. In the survival analysis, we found improved survival since January 1, 1976, indicating improvement in dialysis technique up until that time. The 1, 3, and 5 yr survival were 78%, 47%, and 22% respectively. Only arteriosclerotic heart disease and year of entry were significant risk factors; advancing age over age 70 and in-center dialysis were only of marginal importance. The home patients had fewer dialysis symptoms than in-center patients. Almost all patients lived at home. Five patients (6%) were in nursing homes. Most patients were very satisfied with their lives, regarded their health as better than other 70 year old persons, spent time outdoors, participated in church activities, had active hobbies, enjoyed life very much, and scored high on the Karnofsky activity scale. We conclude older patients are excellent dialysis candidates and it is wrong not to consider them for dialysis.
透析患者的平均年龄正在迅速上升。在我们目前的项目中,所有患者中有20%-25%的人年龄在70岁及以上。我们对所有157名70岁及以上(平均年龄75岁)的患者进行了生存分析,并使用Cox比例风险模型评估了与透析生存相关的风险因素。在一项对所有53名中心透析患者和26名家庭透析患者的患病率研究中,对发病率、生化状态、临床结果和生活满意度进行了评估。在生存分析中,我们发现自1976年1月1日以来生存率有所提高,这表明截至那时透析技术有所改进。1年、3年和5年生存率分别为78%、47%和22%。只有动脉硬化性心脏病和进入年份是显著的风险因素;70岁以上年龄的增长和中心透析仅具有边缘重要性。家庭透析患者的透析症状比中心透析患者少。几乎所有患者都在家中生活。5名患者(6%)住在养老院。大多数患者对自己的生活非常满意,认为自己的健康状况比其他70岁的人更好,在户外活动,参加教会活动,有积极的爱好,非常享受生活,并且在卡诺夫斯基活动量表上得分很高。我们得出结论,老年患者是优秀的透析候选者,不考虑他们进行透析是错误的。