• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年患者的肾移植:益处与风险

Kidney transplantation in older patients: benefits and risks.

作者信息

Rao Venkateswara K

机构信息

Hennepin County Medical Center, Minneapolis, Minnesota 55415, USA.

出版信息

Drugs Aging. 2002;19(2):79-84. doi: 10.2165/00002512-200219020-00001.

DOI:10.2165/00002512-200219020-00001
PMID:11950375
Abstract

The proportion of older patients accepted for dialysis is increasing every year both in the US and abroad. Of the two treatment modalities for end-stage renal disease, i.e. dialysis and transplantation, the latter offers more freedom and is associated with better clinical outcome. Most elderly patients seem to have excellent functional rehabilitation after a kidney transplant. However, in view of the wide gap between the availability of cadaver organs and the people in need, giving the precious organ to the elderly who have a shorter expected lifespan may present an ethical problem. Therefore, it has become increasingly important to offer the kidney to only those who have no significant comorbid conditions or other high risk factors, so as to improve the odds of success after renal transplantation.

摘要

在美国和国外,接受透析治疗的老年患者比例每年都在增加。对于终末期肾病的两种治疗方式,即透析和移植,后者提供了更多的自由,并且与更好的临床结果相关。大多数老年患者在肾移植后似乎有良好的功能康复。然而,鉴于尸体器官的可获得性与有需求的人群之间存在巨大差距,将珍贵的器官给予预期寿命较短的老年人可能会带来伦理问题。因此,只将肾脏提供给那些没有严重合并症或其他高风险因素的人变得越来越重要,以便提高肾移植后的成功率。

相似文献

1
Kidney transplantation in older patients: benefits and risks.老年患者的肾移植:益处与风险
Drugs Aging. 2002;19(2):79-84. doi: 10.2165/00002512-200219020-00001.
2
The impact of comorbid and sociodemographic factors on access to renal transplantation.共病因素和社会人口学因素对肾移植可及性的影响。
JAMA. 1993 Feb 3;269(5):603-8.
3
Do elderly recipients really benefit from kidney transplantation?老年受者真的能从肾移植中获益吗?
Transplant Rev (Orlando). 2015 Oct;29(4):197-201. doi: 10.1016/j.trre.2015.09.002. Epub 2015 Sep 18.
4
Renal transplantation in the older end stage renal disease patient.老年终末期肾病患者的肾移植
Semin Nephrol. 1996 Jul;16(4):353-62.
5
[REIN Report 2011--summary].[2011年肾脏疾病改善全球结果(KDIGO)报告——摘要]
Nephrol Ther. 2013 Sep;9 Suppl 1:S3-6. doi: 10.1016/S1769-7255(13)70036-1.
6
Rates of renal transplantations in the elderly-data from Europe and the US.老年人肾移植率——来自欧洲和美国的数据。
Transplant Rev (Orlando). 2015 Oct;29(4):193-6. doi: 10.1016/j.trre.2015.04.005. Epub 2015 May 6.
7
Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant.透析患者、等待移植的透析患者以及首次尸体器官移植受者的死亡率比较。
N Engl J Med. 1999 Dec 2;341(23):1725-30. doi: 10.1056/NEJM199912023412303.
8
The UNOS Renal Transplant Registry: Review of the Last Decade.美国器官共享联合网络肾脏移植登记处:过去十年回顾
Clin Transpl. 2014:1-12.
9
Preemptive kidney transplantation in elderly recipients with kidneys discarded of very old donors: A good alternative.在老年受者中进行来自极老龄供者废弃肾脏的抢先肾移植:一种不错的选择。
Nefrologia. 2015;35(3):246-55. doi: 10.1016/j.nefro.2015.05.010. Epub 2015 Jun 18.
10
Kidney Transplantation Rates Across Glomerulonephritis Subtypes in the United States.美国各肾小球肾炎亚型的肾移植率。
Transplantation. 2017 Oct;101(10):2636-2647. doi: 10.1097/TP.0000000000001657.

引用本文的文献

1
Dialysis or kidney transplantation in older adults? A systematic review summarizing functional, psychological, and quality of life-related outcomes after start of kidney replacement therapy.老年人应选择透析还是肾移植?一项系统综述总结了肾脏替代治疗开始后的功能、心理及生活质量相关结局。
Int Urol Nephrol. 2022 Nov;54(11):2891-2900. doi: 10.1007/s11255-022-03208-2. Epub 2022 May 6.
2
Kidney transplantation or dialysis in older adults-an interview study on the decision-making process.老年患者的肾移植或透析治疗——一项关于决策过程的访谈研究。
Age Ageing. 2022 Jun 1;51(6). doi: 10.1093/ageing/afac111.
3
Live and deceased donor kidney transplantation in patients aged 75 years and older in the United States.

本文引用的文献

1
Predicting clinical outcome in the elderly renal transplant recipient.
Kidney Int. 2000 May;57(5):2144-50. doi: 10.1046/j.1523-1755.2000.00066.x.
2
Increased immunosuppressive vulnerability in elderly renal transplant recipients.老年肾移植受者免疫抑制易感性增加。
Transplantation. 2000 Mar 15;69(5):885-9. doi: 10.1097/00007890-200003150-00037.
3
A comparison of the effects of dialysis and renal transplantation on the survival of older uremic patients.
Transplantation. 2000 Mar 15;69(5):794-9. doi: 10.1097/00007890-200003150-00020.
4
Int Urol Nephrol. 2005;37(3):641-8. doi: 10.1007/s11255-004-0010-6.
4
Pharmacokinetic considerations relating to tacrolimus dosing in the elderly.与老年人他克莫司给药相关的药代动力学考量
Drugs Aging. 2005;22(7):541-57. doi: 10.2165/00002512-200522070-00001.
5
Drug therapy in transplant recipients: special considerations in the elderly with comorbid conditions.移植受者的药物治疗:合并症老年患者的特殊考量
Drugs Aging. 2004;21(5):323-48. doi: 10.2165/00002512-200421050-00004.
Infectious complications in geriatric renal transplant patients: comparison of two immunosuppressive protocols.老年肾移植患者的感染性并发症:两种免疫抑制方案的比较
Transplantation. 1999 Nov 27;68(10):1496-502. doi: 10.1097/00007890-199911270-00012.
5
A review of quality of life in chronic renal failure.慢性肾衰竭患者生活质量综述。
Pharmacoeconomics. 1997 Aug;12(2 Pt 1):140-60. doi: 10.2165/00019053-199712020-00005.
6
Analysis of factors affecting the outcome of renal transplantation in older people.影响老年人肾移植结局的因素分析
Transplant Proc. 1997 Feb-Mar;29(1-2):261. doi: 10.1016/s0041-1345(96)00087-5.
7
Survival experience among elderly end-stage renal disease patients. A controlled comparison of transplantation and dialysis.老年终末期肾病患者的生存经验。移植与透析的对照比较。
Transplantation. 1995 Dec 27;60(12):1389-94. doi: 10.1097/00007890-199560120-00003.
8
One-hundred and five cadaveric kidney transplants with cyclosporine in recipients more than 60 years of age.105例在60岁以上受者中使用环孢素的尸体肾移植。
Transplant Proc. 1993 Feb;25(1 Pt 2):1323.
9
Renal replacement therapies in the elderly: Part II. Renal transplantation.老年人的肾脏替代治疗:第二部分。肾移植。
Am J Kidney Dis. 1994 Jan;23(1):1-15. doi: 10.1016/s0272-6386(12)80805-5.
10
Renal transplantation in older people.老年人肾移植
Lancet. 1994 Feb 19;343(8895):461-4. doi: 10.1016/s0140-6736(94)92698-0.