Wojtal E, Górewicz R, Borkowski M
Acta Physiol Pol. 1984 Jan-Feb;35(1):72-5.
The purpose of the experiments was to investigate the effect of transient ischaemia on the functional state of skin arteriovenous anastomoses (AVA) and on the development of trophic ulceration after sciatic nerve transection in rabbit. The functional state of AVA (their opening or occlusion) was determined on the basis of gasometric investigations of venous blood oxygenation. The experiments showed that transient ischaemia leads to a marked reduction in blood flow through the open (as the result of sciatic nerve transection) AVA in the ischaemic limb. Vascular dilatation developing until collateral blood flow is established, increased capillary and decreased AVA flow do not prevent the formation of ulceration after sciatic nerve transection but significantly delay its development and alleviate its course.
这些实验的目的是研究短暂性缺血对兔皮肤动静脉吻合支（AVA）功能状态以及坐骨神经横断后营养性溃疡形成的影响。AVA的功能状态（开放或闭塞）是根据静脉血氧合的气体测量研究来确定的。实验表明，短暂性缺血会导致缺血肢体中开放的（由于坐骨神经横断所致）AVA的血流显著减少。在侧支血流建立之前出现的血管扩张、毛细血管血流增加以及AVA血流减少，并不能防止坐骨神经横断后溃疡的形成，但会显著延迟其发展并减轻其进程。
