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Suppression of xenogeneic local graft versus host reaction by rat fetal spleen cells.

作者信息

Skowron-Cendrzak A, Rybczyńska Z, Sajak A, Dobrowolski Z

出版信息

Arch Immunol Ther Exp (Warsz). 1984;32(4):443-6.

PMID:6534317
Abstract

Xenogeneic local graft versus host reaction was induced by the injection of 5 X 10(7) adult rat spleen cells under the capsule of cyclophosphamide-treated adult mice. A significant decrease in the reaction, measured by the kidney enlargement index, was obtained by adding to the reacting cells 5-20% of fetal rat spleen cells. Fetal rat thymocytes of fetal mouse splenocytes were not found to be inhibitory. The suppressive activity of rat spleen cells waned completely on day 3 of the postnatal life.

摘要

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