小鼠胎儿和新生脾细胞对局部移植物抗宿主反应的抑制作用。
Suprression of local graft-versus-host reactions by mouse fetal and newborn spleen cells.
作者信息
Skowron-Cendrzak A, Ptak W
出版信息
Eur J Immunol. 1976 Jun;6(6):451-2. doi: 10.1002/eji.1830060613.
PMID:11102
Abstract
Fetal splenic but not thymic lymphocytes significantly reduce the ability of parenteral adult spleen cells to elicit local graft-versus-host reactions in F1 recipients. This suppressive activity wanes early after birth. There is no requirement for histo compatibility between reacting and suppressor cells.
摘要
胎儿脾脏而非胸腺的淋巴细胞能显著降低成年亲体脾细胞在F1受体中引发局部移植物抗宿主反应的能力。这种抑制活性在出生后早期就会减弱。反应细胞和抑制细胞之间不存在组织相容性的要求。
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