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大鼠的乙醇偏好行为与多巴胺释放

Ethanol preference behaviour and dopamine release in the rat.

作者信息

Schmidt J, Andreas K, Dienel A, Fischer H D, Wustmann C

出版信息

Biomed Biochim Acta. 1984;43(12):1431-4.

PMID:6534381
Abstract

The development of ethanol preference behaviour in rats is connected with a decrease of dopamine release from striatum slices seen after alcohol cessation. The inhibition of dopamine release vanishes spontaneously within a few days. Restitution is highly accelerated by piracetam, exhibiting similarities to posthypoxic membrane damages.

摘要

大鼠乙醇偏好行为的发展与戒酒后脑纹状体切片中多巴胺释放的减少有关。多巴胺释放的抑制在几天内会自发消失。吡拉西坦可显著加速恢复过程,这与缺氧后膜损伤具有相似性。

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