Hopwood D, Logan K R, Coghill G, Bouchier I A
Histochem J. 1977 Mar;9(2):153-61. doi: 10.1007/BF01003627.
The histochemistry of lipids and mucosubstances in normal human oesophageal epithelium were studied in biopsies obtained from 24 patients undergoing investigations of the upper gastro-intestinal tract. Neutral fat droplets, 1-2 mum in diameter, were present in all layers, the greatest number being in the functional layer cells. No unsaturated lipids or fatty acids were demonstrable. Much glycogen was present in the cytoplasm of the prickle and functional cell layers as demonstrated by PAS (and diastase digestion) techniques. The intercellular space of the most superficial of the functional cell layer contained neutral and sialic acid-rich acid mucopolysaccharides. These may be important in protecting the epithelium against physical and chemical trauma.
对24例接受上消化道检查患者的活检组织进行研究，以观察正常人类食管上皮中脂质和黏液物质的组织化学情况。直径为1 - 2微米的中性脂肪滴存在于各层，其中功能层细胞中的数量最多。未检测到不饱和脂质或脂肪酸。采用PAS（及淀粉酶消化）技术证实，棘细胞层和功能细胞层的细胞质中存在大量糖原。功能细胞层最表层的细胞间空间含有中性和富含唾液酸的酸性黏多糖。这些物质可能在保护上皮免受物理和化学损伤方面具有重要作用。
