Asmal A C, Leary W P, Winning T, Dayal B
S Afr Med J. 1978 Feb 4;53(5):181-2.
A 35-year-old patient with Sheehan's syndrome presented with hypothyroidism and hypo-adrenalism despite having received treatment with regular daily L-thyroxine (0,3 mg) and prednisone (30 mg) for the preceding 12 months. Replacement of the prednisone with 37,5 mg cortisone acetate resulted in satisfactory control of the disease. The observations suggest that large doses of prednisone may interfere with thyroxine treatment.
一名患有席汉综合征的35岁患者,尽管在过去12个月中每天规律服用左甲状腺素(0.3毫克)和泼尼松(30毫克)进行治疗,但仍出现甲状腺功能减退和肾上腺功能减退。用37.5毫克醋酸可的松替代泼尼松后,疾病得到了满意的控制。这些观察结果表明,大剂量的泼尼松可能会干扰甲状腺素治疗。