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[关于放射性危害的杂合子β地中海贫血患者]

[The heterozygote beta-thalassemic patient with regard to radiological hazards].

作者信息

Toti A, Nibbio A, Camerini G, Buriani C, Bariani L, Zerbinati C, Cervi P M, Castaldi G

出版信息

Radiol Med. 1984 Jul-Aug;70(7-8):516-9.

PMID:6535170
Abstract

Since anaemia of varying degree is a quite common finding in heterozygous beta-thalassaemia, a research was done to see if beta-thalassaemia heterozygotes occupationally exposed to long-term continuous external radiation should be more susceptible to haematopoietic damage than non thalassaemic subjects. We examined peripheral haematological findings of 20 beta-thalassaemia heterozygotes previously exposed to a mean of 10.7 mSv, compared with 22 non thalassaemic subjects exposed to 6 mSv, and with 50 not exposed beta-thalassaemia heterozygotes. The obtained results suggest that whole-body external irradiation--with the mean doses reported--does not cause noteworthy changes in beta-thalassaemia heterozygotes.

摘要

由于不同程度的贫血在杂合子β地中海贫血中是相当常见的表现,因此开展了一项研究,以观察职业性长期持续暴露于外照射的β地中海贫血杂合子是否比非地中海贫血受试者更容易受到造血损伤。我们检查了20名先前平均暴露于10.7毫希沃特的β地中海贫血杂合子的外周血液学检查结果,并与22名暴露于6毫希沃特的非地中海贫血受试者以及50名未暴露的β地中海贫血杂合子进行比较。所得结果表明,以报告的平均剂量进行全身外照射不会在β地中海贫血杂合子中引起显著变化。

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