Egedahl R, Rice E
IARC Sci Publ. 1984(53):47-55.
Sherritt Gordon Mines Limited established hydrometallurgical nickel refining operations at Fort Saskatchewan, Alberta, in 1954. Records of workers with a minimum of one year's employment with Sherritt Gordon Mines were obtained and identification information as well as details of work history were collected and placed on computer. Cancer cases were identified by matching the study records with the computer listings of the Alberta Cancer Registry. Cancer deaths were verified utilizing record-linkage with death registrations of the Alberta Vital Statistics Division. The files of the Alberta Health Care Insurance Commission were used to ascertain the vital status of past employees of Sherritt Gordon Mines Limited. Among the 993 employees in the nickel refining and maintenance groups at Sherritt Gordon Mines, 30 cases of cancer were identified occurring at 13 diagnostic sites. No neoplasms of the nasal cavities or paranasal sinuses were found in the study population. Two cases of lung cancer were detected among maintenance workers. A single case of renal-cell cancer was diagnosed in the nickel-exposure category as well as in the maintenance group. None of the observed-to-expected cancer incidence ratios at the various diagnostic sites were statistically significant at the p less than 0.05 level.
谢里特·戈登矿业有限公司于1954年在艾伯塔省萨斯喀彻温堡建立了湿法冶金镍精炼厂。获取了在谢里特·戈登矿业公司工作至少一年的工人记录，收集了身份信息以及工作经历细节并录入计算机。通过将研究记录与艾伯塔癌症登记处的计算机列表进行匹配来识别癌症病例。利用与艾伯塔省生命统计部门死亡登记的记录链接来核实癌症死亡情况。艾伯塔省医疗保险委员会的档案用于确定谢里特·戈登矿业有限公司过去员工的生命状态。在谢里特·戈登矿业公司的镍精炼和维护部门的993名员工中，在13个诊断部位发现了30例癌症病例。在研究人群中未发现鼻腔或鼻窦肿瘤。在维护工人中检测到2例肺癌。在镍暴露组和维护组中均诊断出1例肾细胞癌。在各个诊断部位观察到的癌症发病率与预期发病率之比在p小于0.05水平时均无统计学意义。
