铜绿假单胞菌感染小鼠体液免疫反应的调节
Modulation of the humoral response in Pseudomonas aeruginosa-infected mice.
作者信息
Izdebska-Szymona K, Sitnicka E, Nowakowska K, Drela N
出版信息
Arch Immunol Ther Exp (Warsz). 1984;32(6):689-94.
PMID:6536239
Abstract
Kinetics of humoral anti-SRBC response in the host infected with Pseudomonas aeruginosa was investigated. In the course of experimental infection in CFW mice with 0.01 LD50 Pseudomonas aeruginosa 74 followed by immunization with SRBC, inhibition of PFC anti-SRBC production was observed for 5 days after infection. In the case of infection with 0.1 LD50 P. aeruginosa 74 stimulation of anti-SRBC PFC production was observed for 6 days after infection.
摘要
研究了感染铜绿假单胞菌的宿主体液抗绵羊红细胞（SRBC）反应的动力学。在用0.01 LD50铜绿假单胞菌74感染CFW小鼠并随后用SRBC免疫的实验感染过程中，感染后5天观察到抗SRBC的空斑形成细胞（PFC）产生受到抑制。在用0.1 LD50铜绿假单胞菌74感染的情况下，感染后6天观察到抗SRBC PFC产生受到刺激。
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