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[摩洛哥的鼻咽癌:流行病学研究方法]

[Cancer of the nasopharynx in Morocco: epidemiological approach].

作者信息

el Gueddari B, el Hafed A, Bouih A, el Morchid M, Kahlain A

出版信息

IARC Sci Publ. 1984(63):513-24.

PMID:6536623
Abstract

Between 1 April 1980 and 30 Septembre 1983, 412 cases of nasopharyngeal carcinoma were seen at the Bergonié Cancer Centre in Casablanca (the sole centre in the country), representing 4.76% of all malignant tumours diagnosed in that period. This percentage is low, since the majority of these tumours are not diagnosed outside the big towns but indicates that Morocco is an area of moderate incidence for this cancer. We have studied the epidemiological aspects of our series; there is a predominance of males (sex ratio, 2.25: M:F); the average age is 43 years with a large proportion of young people (24.6% are less than 30 years old). A high incidence is observed in the north of the country, where, however, more medical facilities are available. Advanced tumours are common: 15% cannot be treated; 32.5% are in stage T4, and 70% have metastatic cervical nodes. Pathologically, 90% are undifferentiated carcinomas of the nasopharyngeal type. The results of the immunological study do not exclude a viral (Epstein-Barr virus) contribution. Prospective epidemiological studies are needed to elucidate the exact profile of this cancer in our country.

摘要

1980年4月1日至1983年9月30日期间,卡萨布兰卡的贝戈涅癌症中心(该国唯一的中心)共收治了412例鼻咽癌患者,占该时期确诊的所有恶性肿瘤的4.76%。这个比例较低,因为这些肿瘤大多数在大城市以外未被诊断出来,但这表明摩洛哥是这种癌症发病率中等的地区。我们研究了我们这组病例的流行病学情况;男性占主导(性别比为2.25:男:女);平均年龄为43岁,年轻人占很大比例(24.6%小于30岁)。在该国北部观察到高发病率,然而,那里有更多的医疗设施。晚期肿瘤很常见:15%无法治疗;32.5%处于T4期,70%有颈部转移性淋巴结。病理上,90%是鼻咽型未分化癌。免疫学研究结果不排除病毒(爱泼斯坦-巴尔病毒)的作用。需要进行前瞻性流行病学研究以阐明我国这种癌症的确切情况。

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[Cancer of the nasopharynx in Morocco: epidemiological approach].[摩洛哥的鼻咽癌:流行病学研究方法]
IARC Sci Publ. 1984(63):513-24.
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[Epidemiologic approach to cancer of the nasopharynx in Morocco].[摩洛哥鼻咽癌的流行病学研究方法]
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引用本文的文献

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High serum levels of soluble CD40-L in patients with undifferentiated nasopharyngeal carcinoma: pathogenic and clinical relevance.未分化鼻咽癌患者血清中可溶性CD40配体水平升高:致病及临床意义
Infect Agent Cancer. 2007 Mar 1;2:5. doi: 10.1186/1750-9378-2-5.
2
Antibody responses to recombinant Epstein-Barr virus antigens in nasopharyngeal carcinoma patients: complementary test of ZEBRA protein and early antigens p54 and p138.鼻咽癌患者对重组爱泼斯坦-巴尔病毒抗原的抗体反应:ZEBRA蛋白与早期抗原p54和p138的补充检测
J Clin Microbiol. 2001 Sep;39(9):3164-70. doi: 10.1128/JCM.39.9.3164-3170.2001.