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[从猪分离出的鸟分枝杆菌和非典型分枝杆菌各菌株的生物学特性及变应原特性]

[Biological and allergenic properties of various strains of Mycobacterium avium and atypical Mycobacterium isolated from swine].

作者信息

Hołub M

出版信息

Pol Arch Weter. 1984;24(1):33-49.

PMID:6537487
Abstract

Thirty two strains of Myc. avium showing typical or atypical cultural and biochemical properties, and 8 strains of atypical bacilli, belonging to II, III and IV Runyon's groups, were inoculated into guinea-pigs, rabbits and chickens. All the Myc. avium strains were not pathogenic for guinea-pigs but were very virulent to rabbits and chickens. The atypical bacilli were not pathogenic for all the animals to be used, but some of them induced tuberculin allergy. Myc. avium, Myc. fortuitum, strain of scotochromogenic bacilli--all isolated from pigs and Myc. avium D4, were used for study of the sensitizing properties. The experiments were performed on albinotic guinea-pigs sensitized intramuscularly and young pigs sensitized per os. The results showed that avian bacilli possessed much stronger sensitizing properties than Myc. fortuitum or scotochromogenic bacilli. Tuberculin allergy caused by atypical bacilli usually lasts for a short time. However, infection of pigs with atypical bacilli can sometimes allergical diagnosis of swine tuberculosis difficult.

摘要

将32株表现出典型或非典型培养及生化特性的鸟分枝杆菌,以及属于鲁尼恩分类法第二、三、四组的8株非典型杆菌接种到豚鼠、兔子和鸡体内。所有鸟分枝杆菌菌株对豚鼠无致病性,但对兔子和鸡具有很强的毒力。非典型杆菌对所有实验动物均无致病性,但其中一些可诱导结核菌素过敏。从猪体内分离出的鸟分枝杆菌、偶然分枝杆菌、暗产色杆菌菌株以及鸟分枝杆菌D4用于致敏特性研究。实验在肌肉注射致敏的白化豚鼠和经口致敏的幼猪身上进行。结果表明,禽型杆菌的致敏特性比偶然分枝杆菌或暗产色杆菌强得多。非典型杆菌引起的结核菌素过敏通常持续时间较短。然而,猪感染非典型杆菌有时会给猪结核病的变态反应诊断带来困难。

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