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[从猪分离出的各种禽型和非典型分枝杆菌的生物学和变应原特性研究]

[Studies on the biologic and allergenic properties of various avian and atypical Mycobacteria isolated from swine].

作者信息

Hołub M

出版信息

Pol Arch Weter. 1984;24(1):33-49.

PMID:6571464
Abstract

Thirty two strains of Myc. avium showing typical or atypical cultural and biochemical properties, and 8 strains of atypical bacilli, belonging to II, III and IV Runyon's groups, were inoculated into guinea-pigs, rabbits and chickens. All the Myc. avium strains were not pathogenic for guinea-pigs but were very virulent to rabbits and chickens. The atypical bacilli were not pathogenic for all the animals to be used, but some of them induced tuberculin allergy. Myc. avium, Myc. fortuitum, strain of scotochromogenic bacilli--all isolated from pigs and Myc. avium D4, were used for study of the sensitizing properties. The experiments were performed on albinotic guinea-pigs sensitized intramuscularly and young pigs sensitized per os. The results showed that avian bacilli possessed much stronger sensitizing properties than Myc. fortuitum or scotochromogenic bacilli. Tuberculin allergy caused by atypical bacilli usually lasts for a short time. However, infection of pigs with atypical bacilli can sometimes allergical diagnosis of swine tuberculosis difficult.

摘要

将32株表现出典型或非典型培养及生化特性的鸟分枝杆菌,以及8株属于鲁尼恩分类法II、III和IV组的非典型杆菌,接种到豚鼠、兔子和鸡体内。所有鸟分枝杆菌菌株对豚鼠无致病性,但对兔子和鸡具有很强的毒力。非典型杆菌对所有受试动物均无致病性,但其中一些会引起结核菌素过敏。鸟分枝杆菌、偶然分枝杆菌、均从猪分离出的暗产色杆菌菌株以及鸟分枝杆菌D4,用于致敏特性研究。实验在肌肉注射致敏的白化豚鼠和经口致敏的幼猪身上进行。结果表明,禽分枝杆菌的致敏特性比偶然分枝杆菌或暗产色杆菌强得多。非典型杆菌引起的结核菌素过敏通常持续时间较短。然而,猪感染非典型杆菌有时会使猪结核病的变态反应诊断变得困难。

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