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[进行性肌营养不良患儿及携带者的血液肌红蛋白]

[Blood myoglobin in children with progressive muscular dystrophy and in carriers].

作者信息

Calandi C, Baretti S, Pacciani G, Bagni P, Borsotti M, Tozzi P, Adami Lami C

出版信息

Quad Sclavo Diagn. 1984 Dec;20(4):391-8.

PMID:6537549
Abstract

We studied the behaviour of serum myoglobin in 32 children affected by Duchenne muscular dystrophy, in 30 mothers (10 definite carriers and 20 possible carriers), in 5 sisters (possible carriers) and in 40 healthy women (control). The serum myoglobin was always increased in the patients affected by Duchenne muscular dystrophy; the greatest values were in the patients who were still ambulant, with a behaviour similar to creatine kinase. In the carriers the myoglobinemia showed a significant increase in definite carriers, while there was no significant difference between the possible carriers and the controls.

摘要

我们研究了32例杜氏肌营养不良患儿、30名母亲(10名确诊携带者和20名可能携带者)、5名姐妹(可能携带者)以及40名健康女性(对照组)血清肌红蛋白的情况。杜氏肌营养不良患者的血清肌红蛋白总是升高的;最高值出现在仍能行走的患者中,其变化规律与肌酸激酶相似。在携带者中,确诊携带者的肌红蛋白血症显著升高,而可能携带者与对照组之间无显著差异。

相似文献

1
[Blood myoglobin in children with progressive muscular dystrophy and in carriers].[进行性肌营养不良患儿及携带者的血液肌红蛋白]
Quad Sclavo Diagn. 1984 Dec;20(4):391-8.
2
Serum myoglobin in muscular dystrophy.肌营养不良症中的血清肌红蛋白。
Muscle Nerve. 1980 May-Jun;3(3):221-6. doi: 10.1002/mus.880030306.
3
Serum myoglobin in Duchenne muscular dystrophy carrier detection: a comparison with creatine kinase and hemopexin using logistic discrimination.
Am J Med Genet. 1984 Jun;18(2):279-87. doi: 10.1002/ajmg.1320180212.
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Serum creatine kinase and pyruvate kinase in Duchenne muscular dystrophy carrier detection.杜兴氏肌营养不良症携带者检测中的血清肌酸激酶和丙酮酸激酶
Muscle Nerve. 1979 Sep-Oct;2(5):329-39. doi: 10.1002/mus.880020503.
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Duchenne muscular dystrophy: does serum myoglobin correlate with serum creatine kinase?
Muscle Nerve. 1981 May-Jun;4(3):257.
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Hereditary progressive muscular dystrophies: serum myoglobin pattern in patients with different types of muscular dystrophies.
Clin Physiol Biochem. 1989;7(1):40-6.
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[Evaluation of serum pyruvate kinase in patients with Duchenne's muscular dystrophy and carriers. Comparison with other enzyme determinations].[杜兴氏肌营养不良症患者及携带者血清丙酮酸激酶的评估。与其他酶测定的比较]
Minerva Pediatr. 1981 May 31;33(10):453-64.
8
[Genetics and clinical types of progressive muscular dystrophy; creatine kinase and myoglobin as biochemical indices of the disease].
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9
Myoglobinemia in Duchenne muscular dystrophy carriers.杜氏肌营养不良症携带者的肌红蛋白血症
Brain Dev. 1980;2(1):87-8. doi: 10.1016/s0387-7604(80)80012-x.
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Serum myoglobin in muscular dystrophy and carrier detection.肌营养不良症中的血清肌红蛋白及携带者检测。
J Neurol Sci. 1981 Sep;51(3):411-26. doi: 10.1016/0022-510x(81)90118-0.