杜氏肌营养不良症携带者的肌红蛋白血症

Myoglobinemia in Duchenne muscular dystrophy carriers.

作者信息

Ando T, Kato T, Ohsawa M, Fukuyama Y

出版信息

Brain Dev. 1980;2(1):87-8. doi: 10.1016/s0387-7604(80)80012-x.

Abstract

We have carried out serum assays for myoglobin in parallel with the determination of serum CPK activity to assess its usefulness in raising the detectability rate of Duchenne muscular dystrophy carriers. Of the 14 carriers, ten (71.4%) had high serum levels of myoglobin and nine (64.3%) showed increased serum CPK levels. Either parameter revealed elevation in 11 (78.6%) of the 14 cases studied. Serum myoglobin determination is of noticeable value in the detection of Duchenne muscular dystrophy carriers.

摘要

我们同时进行了血清肌红蛋白检测和血清肌酸磷酸激酶（CPK）活性测定，以评估其在提高杜兴氏肌营养不良症携带者检出率方面的作用。在14名携带者中，10名（71.4%）血清肌红蛋白水平较高，9名（64.3%）血清CPK水平升高。在研究的14例病例中，11例（78.6%）的任何一项指标都显示升高。血清肌红蛋白测定在杜兴氏肌营养不良症携带者的检测中具有显著价值。