恶性肾上腺皮质癌单独分泌醛固酮。

Levine D S, Fischer D G, Forman B H

Yale J Biol Med. 1984 Nov-Dec;57(6):833-41.

A 45-year-old female developed hypertension and hypokalemia. Elevated plasma aldosterone and suppressed plasma renin levels were measured with no evidence for glucocorticoid or androgen abnormalities. A left adrenal tumor was removed that showed histologic criteria for malignancy. It is commonly taught that malignant adrenal tumors are recognized by their multiple hormone production. However, isolated aldosterone production by a carcinoma can occur and requires close follow-up observation and therapy for this highly malignant tumor.

一名45岁女性出现高血压和低钾血症。检测发现血浆醛固酮水平升高，血浆肾素水平受抑制，且无糖皮质激素或雄激素异常的证据。切除了左侧肾上腺肿瘤，该肿瘤显示出恶性的组织学标准。通常认为恶性肾上腺肿瘤可通过多种激素分泌来识别。然而，癌肿可单独分泌醛固酮，对于这种高度恶性肿瘤需要密切随访观察及治疗。