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氦氧混合气体呼吸对机体运动适应的影响。

Effect of breathing of a helium-oxygen mixture on the adaptation of the organism to exercise.

作者信息

Debiński W, Kłossowski M, Gembicka D

出版信息

Acta Physiol Pol. 1984 May-Jun;35(3):285-92.

PMID:6537722
Abstract

The reported investigations were carried out on 17 healthy men aged 20-27 years subjected to a 15 minute submaximal exercise on an Elema-Schonander cycle ergometer while breathing ambient air or a helium-oxygen mixture (O2 20% and He 80%). During the exercise test the heart rate was recorded from the ECG tracings, with the respiratory rate and respiratory volume, minute ventilation and arterial blood pressure. The concentrations of lactate (LA), pyruvate (PA) and glucose were determined in the serum of venous blood obtained before and 3 minutes after the exercise. Favourable changes of the reaction of the organism to exercise were observed while the subjects breathed the helium-oxygen mixture. The minute ventilation increased owing to increased respiratory volume, and the exercise caused lower rises in LA, PA and the LA/PA ratio. This may suggest a reduction of respiration cost and a decrease of anaerobic metabolism under these conditions.

摘要

所报告的研究是对17名年龄在20至27岁的健康男性进行的。这些男性在Elema-Schonander自行车测力计上进行15分钟的次最大运动,同时呼吸环境空气或氦氧混合气体(氧气20%,氦气80%)。在运动测试期间,通过心电图记录心率,并记录呼吸频率、呼吸量、分钟通气量和动脉血压。在运动前和运动后3分钟采集静脉血血清,测定乳酸(LA)、丙酮酸(PA)和葡萄糖的浓度。当受试者呼吸氦氧混合气体时,观察到机体对运动的反应有良好变化。分钟通气量因呼吸量增加而增加,运动导致LA、PA和LA/PA比值的升高幅度较小。这可能表明在这些条件下呼吸成本降低,无氧代谢减少。

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