Quinn J P, Weinstein R A, Caplan L R
Neurology. 1984 Jan;34(1):108-9. doi: 10.1212/wnl.34.1.108.
We describe eosinophilic meningitis associated with ibuprofen therapy in a young woman who had no evidence of underlying illness. Discontinuation of ibuprofen was followed by prompt resolution of symptoms and disappearance of eosinophils from the CSF. Ibuprofen has been implicated previously in only five cases of aseptic meningitis--all in patients with an underlying autoimmune disease. No drug has been implicated previously as a cause of eosinophilic meningitis to our knowledge.
我们描述了一名无潜在疾病证据的年轻女性中与布洛芬治疗相关的嗜酸性粒细胞性脑膜炎。停用布洛芬后症状迅速缓解，脑脊液中的嗜酸性粒细胞消失。布洛芬此前仅与5例无菌性脑膜炎病例有关——所有病例均为患有潜在自身免疫性疾病的患者。据我们所知，此前尚无药物被认为是嗜酸性粒细胞性脑膜炎的病因。
