Bansal Sharad, Gupta Mukesh, Sharma Deepak, Bansal Shweta
Department of Pediatrics, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India.
Department of Neonatology, Fernandez Hospital, Hyderguda, Hyderabad, Andhra Pradesh, India.
Clin Med Insights Pediatr. 2014 Feb 18;8:3-4. doi: 10.4137/CMPed.S13829. eCollection 2014.
Eosinophilic meningoencephalitis is based on clinical manifestations and microscopic identification of eosinophils present in cerebrospinal fluid (CSF). It is caused by a variety of helminthic infections with most common being angiostrongyliasis, gnathostomiasis, toxocariasis, cysticercosis, schistosomiasis, baylisascariasis, and paragonimiasis. Many case reports are there in which parasites have been found responsible, but there are rare reports of CSF eosinophilia associated with the use of drugs. We report a case of drug-induced (ibuprofen) eosinophilic meningitis in a healthy female who presented to us with severe headache and improved dramatically after drug withdrawal.
嗜酸性粒细胞性脑膜脑炎是基于临床表现以及对脑脊液（CSF）中嗜酸性粒细胞的显微镜鉴定。它由多种蠕虫感染引起，最常见的是广州管圆线虫病、颚口线虫病、弓蛔虫病、囊尾蚴病、血吸虫病、贝利斯蛔虫病和肺吸虫病。有许多病例报告发现寄生虫是病因，但与药物使用相关的脑脊液嗜酸性粒细胞增多的报告却很少。我们报告一例健康女性因服用布洛芬导致的嗜酸性粒细胞性脑膜炎，该患者因严重头痛前来就诊，停药后病情显著改善。
