Gorelick P B, Caplan L R, Hier D B, Parker S L, Patel D
Neurology. 1984 Jan;34(1):54-9. doi: 10.1212/wnl.34.1.54.
We compared clinical and angiographic features of 26 white and 45 black patients with symptomatic occlusive cerebrovascular disease. White patients had more transient ischemic attacks, carotid bruits, and more severe occlusive disease of the internal carotid artery origin. Blacks had more severe disease of the middle cerebral artery stem and supraclinoid internal carotid arteries. Differences were not explained by racial differences in the prevalence of hypertension, diabetes, hypercholesterolemia, or ischemic heart disease. Since the middle cerebral artery lesions in blacks do not correlate with other accepted epidemiologic, clinical, and laboratory markers of atherosclerosis, the lesions may arise from a disorder that differs from atherosclerosis.
我们比较了26名白人患者和45名黑人患者的临床及血管造影特征，这些患者均患有症状性闭塞性脑血管疾病。白人患者有更多的短暂性脑缺血发作、颈动脉杂音，以及更严重的颈内动脉起始部闭塞性疾病。黑人患者大脑中动脉主干和床突上段颈内动脉的疾病更为严重。种族差异在高血压、糖尿病、高胆固醇血症或缺血性心脏病患病率方面无法解释这些差异。由于黑人患者大脑中动脉病变与动脉粥样硬化的其他公认的流行病学、临床及实验室指标不相关，这些病变可能源于一种不同于动脉粥样硬化的疾病。
