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无症状性闭塞性脑血管疾病的临床与血管造影比较

Clinical and angiographic comparison of asymptomatic occlusive cerebrovascular disease.

作者信息

Gorelick P B, Caplan L R, Langenberg P, Hier D B, Pessin M, Patel D, Taber J

机构信息

Department of Neurology, Michael Reese Hospital, Chicago, IL 60616.

出版信息

Neurology. 1988 Jun;38(6):852-8. doi: 10.1212/wnl.38.6.852.

Abstract

We compared clinical and arteriographic features in 106 patients with symptomatic unilateral carotid territory occlusive disease to determine the frequency and distribution of occlusive arterial lesions in asymptomatic vessels. Among black patients who were predominantly from Chicago, young, and female, there were fewer transient ischemic attacks and myocardial infarcts, less claudication, and more asymptomatic lesions of the supraclinoid internal carotid artery, anterior cerebral artery stem, and the middle cerebral artery stem. Among white patients predominantly from New England, elderly, and male, there was more frequent and severe occlusive asymptomatic disease at extracranial carotid and vertebral artery sites. Knowledge of the distribution of asymptomatic lesions will help guide evaluation and treatment strategies for patients with occlusive cerebrovascular disease.

摘要

我们比较了106例有症状的单侧颈动脉区域闭塞性疾病患者的临床和血管造影特征,以确定无症状血管中闭塞性动脉病变的频率和分布。在主要来自芝加哥、年轻且为女性的黑人患者中,短暂性脑缺血发作和心肌梗死较少,跛行较少,而床突上段颈内动脉、大脑前动脉主干和大脑中动脉主干的无症状病变较多。在主要来自新英格兰、老年且为男性的白人患者中,颅外颈动脉和椎动脉部位的无症状闭塞性疾病更为频繁和严重。了解无症状病变的分布将有助于指导闭塞性脑血管疾病患者的评估和治疗策略。

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