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评估儿童维生素A状况时餐后视黄醇、视黄醇结合蛋白和类胡萝卜素血浓度的意义

Significance of postprandial blood concentrations of retinol, retinol-binding protein, and carotenoids when assessing the vitamin A status of children.

作者信息

Mejía L A, Pineda O, Noriega J F, Benítez J, Falla G

出版信息

Am J Clin Nutr. 1984 Jan;39(1):62-5. doi: 10.1093/ajcn/39.1.62.

DOI:10.1093/ajcn/39.1.62
PMID:6537871
Abstract

The effect of ingesting a breakfast rich in vitamin A on postprandial blood serum concentration of retinol, retinol-binding protein, and carotenoids has been investigated in children between 5 and 8 yr of age. They were divided by age in two groups (5 to 6 and 7 to 8 yr) and then randomly assigned in three groups to be studied cross-sectionally immediately before and at 2 and 4 h after the ingestion of a meal containing 337 micrograms of retinol equivalents (48% as retinol and 52% as carotenoids). The ingestion of breakfast did not alter significantly (p greater than 0.05) the postprandial serum concentrations of retinol, retinol-binding protein; or carotenoids in any of the age groups. These results indicate that up to 4 h the postprandial blood serum concentrations of these parameters are representative of their corresponding basal concentrations. Therefore, in practice and particularly under field survey conditions, the blood samples required to assess the vitamin A status of children can be obtained either fasting or within 4 h after breakfast without altering the results.

摘要

对5至8岁儿童摄入富含维生素A的早餐后,血清视黄醇、视黄醇结合蛋白和类胡萝卜素的餐后浓度的影响进行了研究。他们按年龄分为两组(5至6岁和7至8岁),然后随机分为三组,在摄入含有337微克视黄醇当量(48%为视黄醇,52%为类胡萝卜素)的一餐之前、之后2小时和4小时进行横断面研究。早餐的摄入在任何年龄组中均未显著改变(p>0.05)视黄醇、视黄醇结合蛋白或类胡萝卜素的餐后血清浓度。这些结果表明,在长达4小时内,这些参数的餐后血清浓度代表了其相应的基础浓度。因此,在实践中,特别是在现场调查条件下,评估儿童维生素A状态所需的血样可以在空腹时或早餐后4小时内采集,而不会改变结果。

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