Oksche A, Liesner R, Tigges J, Tigges M
Cell Tissue Res. 1984;235(2):467-9. doi: 10.1007/BF00217876.
Complex intracellular inclusion bodies of the Biondi type were observed in the choroidal epithelium (choroid plexus of the lateral ventricle) of a 43-year-old male chimpanzee. The specific components of these inclusions are bundles of filaments 8-15 nm in diameter, which are associated with lipid droplets and a wide variety of unidentified inclusions of differing electron density. Biondi bodies are characteristic inclusions of the choroid plexus of aged humans but have been claimed to be absent from the choroidal epithelium of senescent animals including nonhuman primates. The present finding of Biondi body-like inclusions in an aged chimpanzee underscores the usefulness of nonhuman primates as models for studies of aging, seeking to gain a better understanding of gerontological aspects of the human brain.
在一只43岁雄性黑猩猩的脉络丛上皮（侧脑室脉络丛）中观察到了比昂迪型复杂的细胞内包涵体。这些包涵体的特定成分是直径为8 - 15纳米的细丝束，它们与脂滴以及各种电子密度不同的未鉴定包涵体相关。比昂迪体是老年人脉络丛的特征性包涵体，但据称在包括非人灵长类动物在内的衰老动物的脉络丛上皮中不存在。在一只老年黑猩猩中发现类似比昂迪体的包涵体，突出了非人灵长类动物作为衰老研究模型的有用性，有助于更好地理解人类大脑的老年学方面。
