Martens U, Klingmüller G
Int J Lepr Other Mycobact Dis. 1984 Mar;52(1):55-60.
Although the grenz zone is indeed free of typical leprosy cells with giant lysosomes, it is not free from leprosy bacilli--these are found in slightly infested macrophages and fibroblasts. For that reason, it would be much clearer if we simply called this region the subepidermal grenz zone of lepromatous leprosy. The subepidermal grenz zone is not pathognomonic of leprosy since grenz zones can be found in other diseases as well. Whereas the grenz zone is typical in lepromatous leprosy, it is not necessarily characteristic of the borderline or the tuberculoid form of the disease. The light and electron microscopical structure of the grenz zone shows that the formation of the subepidermal grenz zone cannot be explained by any particular pathogenetic principle on which therapy can be based.
虽然无浸润带确实没有带有巨大溶酶体的典型麻风细胞，但并非没有麻风杆菌——在轻度受侵的巨噬细胞和成纤维细胞中可发现这些杆菌。因此，如果我们简单地将这个区域称为瘤型麻风的表皮下无浸润带，会更加清晰。表皮下无浸润带并非麻风所特有，因为在其他疾病中也可发现无浸润带。虽然无浸润带在瘤型麻风中很典型，但它不一定是该疾病边缘型或结核样型的特征。无浸润带的光镜和电镜结构表明，表皮下无浸润带的形成无法用任何可作为治疗依据的特定发病原理来解释。
