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[家兔体力过度消耗及实验性神经症过程中额叶皮质和腹内侧下丘脑的功能状态]

[Functional state of the frontal cortex and ventromedial hypothalamus during physical overexertion and experimental neurosis in the rabbit].

作者信息

Boev V M, San'kov A N, Sidorov S V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Jan-Feb;34(1):146-50.

PMID:6538736
Abstract

A change of excitability, pO2 and local cortical blood flow under a long-term maximum physical load and in conditions of experimental neurosis, was investigated in rabbits with electrodes implanted in the frontal cortex and ventromedial hypothalamus. It was found that functional activity of these structures under physical orverstrain rises as the blood flow and pO2 increase, and the excitability also increases. In experimental neurosis, a discoordination in functioning of the cortex and hypothalamus is observed. Relative stabilization of the functional state of tested structures, observed during physical overstrain, is absent in conditions of experimental neurosis.

摘要

对电极植入额叶皮质和腹内侧下丘脑的家兔,研究了长期最大体力负荷及实验性神经症状态下兴奋性、氧分压(pO2)和局部皮质血流量的变化。结果发现,在体力过度疲劳时,这些结构的功能活动随血流量和pO2的增加而增强,兴奋性也增加。在实验性神经症中,观察到皮质和下丘脑功能失调。在体力过度疲劳时所观察到的受试结构功能状态的相对稳定,在实验性神经症状态下并不存在。

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