Vela A, Rieser J C, Campbell D G
Ophthalmology. 1984 Apr;91(4):332-7. doi: 10.1016/s0161-6420(84)34287-7.
Three families with peripheral iris and ciliary body cysts are described. The cysts were multiple in 10 of the 11 affected patients, and they were bilateral in 8 of the 11. Angle closure glaucoma secondary to the cysts was present in 4 of the 11 cases. The management of this glaucoma requires a high index of suspicion, careful gonioscopic evaluation and proper medical and/or surgical treatment. Laser therapy for the angle closure caused by pigmented cysts may be curative. Nonpigmented ciliary body cysts are refractory to argon laser treatment and carry a poor prognosis. The cases described suggest an autosomal dominant hereditary pattern. The importance of examination and follow up of healthy relatives of patients with iris and ciliary body cysts is stressed, as early detection and treatment by laser cystotomy may prevent or cure angle closure glaucoma if the disease is diagnosed prior to the establishment of synechial closure.
本文描述了三个患有周边虹膜和睫状体囊肿的家系。11例受影响患者中有10例囊肿为多发性，11例中有8例为双侧性。11例中有4例因囊肿继发闭角型青光眼。这种青光眼的治疗需要高度的怀疑指数、仔细的前房角镜评估以及适当的药物和/或手术治疗。色素性囊肿引起的闭角型青光眼采用激光治疗可能治愈。非色素性睫状体囊肿对氩激光治疗无效且预后较差。所描述的病例提示为常染色体显性遗传模式。强调了对虹膜和睫状体囊肿患者健康亲属进行检查和随访的重要性，因为如果在虹膜粘连形成之前诊断出该病，通过激光囊肿切开术进行早期检测和治疗可能预防或治愈闭角型青光眼。
