Bentvelzen P
Eur J Cancer Clin Oncol. 1984 Apr;20(4):567-71. doi: 10.1016/0277-5379(84)90244-x.
Cellular DNA of the inbred mouse strains BALB/c, C3Hf, C57BL, CBA, DBAf , GRS and ND2 and the inbred rat strains BN, SD and WAG was shown to oncogenically transform murine fibroblasts of the continuous cell line BALB/3T3. Subcutaneous inoculation of transformed cells into BALB/c mice led to the rapid development of sarcomas. For transformation the DNA had to be fragmented to a size smaller than 23 kilobase pairs (kbp), with a lower limit of 6.5 kbp. No transforming virus could be rescued from the transformed lines by infection with a murine leukemia virus.
近交系小鼠品系BALB/c、C3Hf、C57BL、CBA、DBAf、GRS和ND2以及近交系大鼠品系BN、SD和WAG的细胞DNA被证明可致癌转化连续细胞系BALB/3T3的鼠成纤维细胞。将转化细胞皮下接种到BALB/c小鼠体内会导致肉瘤迅速发展。为了实现转化，DNA必须被片段化为小于23千碱基对（kbp）的大小，下限为6.5 kbp。通过用鼠白血病病毒感染，无法从转化细胞系中拯救出转化病毒。
