Bobba V R, Krishnamurthy G T, Kingston E, Turner F E, Brown P H, Langrell K
J Nucl Med. 1984 Jan;25(1):21-4.
A study was undertaken to establish the pattern of gallbladder emptying in normal subjects and in patients with gallstones, using a fatty meal as stimulus to release endogenous cholecystokinin. The time from meal ingestion to beginning of gallbladder emptying (latent period), the total duration of emptying (ejection period), degree of emptying (ejection fraction), and the rate of emptying (ejection fraction/ejection period) were measured noninvasively by a nongeometric scintigraphic technique. The mean latent period and ejection rate were similar in normal subjects and patients with gallstones, but the mean ejection period and ejection fraction were significantly reduced in the patients. This study suggests that for an identical stimulus, the gallbladder in cholelithiasis begins to empty at the normal time but empties for a shorter duration; the result is a reduction of ejection fraction but not of ejection rate.
进行了一项研究，以确定正常受试者和胆结石患者胆囊排空的模式，使用脂肪餐作为刺激来释放内源性胆囊收缩素。通过非几何闪烁扫描技术以非侵入性方式测量从进食到胆囊排空开始的时间（潜伏期）、排空的总持续时间（射血期）、排空程度（射血分数）和排空速率（射血分数/射血期）。正常受试者和胆结石患者的平均潜伏期和射血速率相似，但患者的平均射血期和射血分数显著降低。这项研究表明，对于相同的刺激，胆石症患者的胆囊在正常时间开始排空，但排空持续时间较短；结果是射血分数降低，而射血速率未降低。
