Schulte W, Neus H, Thönes M, von Eiff A W
Basic Res Cardiol. 1984 Jan-Feb;79(1):9-16. doi: 10.1007/BF01935802.
Blood pressure variability under basal conditions and blood pressure reactivity to emotional stress were studied in 38 hypertensives and 13 normotensives. Systolic basal blood pressure variability correlated with systolic blood pressure reactivity. Variability increased with higher basal blood pressure. Thus in the hypertension group the blood pressure variability was greater than in the normotension group. Besides, the hypertension group showed a greater reactivity of systolic blood pressure to emotional stress, too. An influence of age on basal blood pressure, blood pressure variability, and reactivity could be evaluated; but no influence of sex on these parameters was detected. The results indicate that variability and reactivity of blood pressure can be referred to a common central nervous blood-pressure-regulating mechanism. As both parameters are increased in hypertension, a greater lability of blood pressure must be assumed. This greater lability may be attributed to a stronger neurogenic influence or to structural changes of peripheral blood vessels.
对38名高血压患者和13名血压正常者进行了基础条件下的血压变异性以及情绪应激时血压反应性的研究。收缩压基础血压变异性与收缩压反应性相关。变异性随基础血压升高而增加。因此，高血压组的血压变异性大于血压正常组。此外，高血压组的收缩压对情绪应激的反应性也更高。可以评估年龄对基础血压、血压变异性和反应性的影响；但未检测到性别对这些参数的影响。结果表明，血压的变异性和反应性可归因于一种共同的中枢神经血压调节机制。由于高血压时这两个参数均升高，因此必须假定血压具有更大的不稳定性。这种更大的不稳定性可能归因于更强的神经源性影响或外周血管的结构变化。
