Zamenhof S, van Marthens E
Biol Neonate. 1984;45(6):296-8. doi: 10.1159/000242020.
The present work is concerned with the effect of natural litter size in the rat on the brain and body parameters of individual newborns, with particular reference to those newborns that were 'outstanding' (i.e., had parameters higher than mean +/- 2 SD). Correlations between litter size on one side, and length of gestation, number of stillborns, maternal weight at conception and maternal food consumption were also studied. To our knowledge, no previous report presented a similar integrated study on such a large number of rats (288 litters, 2,725 newborns) and wide range of litter size (2-17).
本研究关注大鼠自然窝仔数对单个新生仔鼠大脑和身体参数的影响,尤其关注那些“突出”的新生仔鼠(即参数高于均值±2标准差)。同时还研究了窝仔数与妊娠期长度、死产数、受孕时母体体重以及母体食物消耗量之间的相关性。据我们所知,此前没有报告针对如此大量的大鼠(288窝,2725只新生仔鼠)以及如此广泛的窝仔数范围(2 - 17只)进行过类似的综合研究。